CADESORB®

In some wounds, even after seemingly successfully overcoming all obstacles to the healing process, successful healing does not occur. One of the most important reasons for impeded healing of an otherwise clean wound may be a disturbed balance of protease activity. CADESORB is an ointment that controls the local pH in the wound, regulates the activity of proteases and thus promotes wound healing. CADESORB is primarily intended for clean wounds that do not show progress, but can also be used on wounds with moist necrotic tissue or wounds with secretions. It is not suitable for infected wounds. CADESORB is used in combination with a compression bandage.

Regulates local pH1

  • CADESORB locally lowers the pH in the wound by ion exchange
  • The process of lowering the pH in the wound decreases the activity of proteases, which is beneficial for the formation of new tissue2,3
  • Works effectively for 3 days

Regulates protease activity

  • Regulates protease activity to protect the extracellular matrix in the wound
  • CADESORB abrogates the activity of quaternary proteases that cause a prolonged inflammatory phase and reduced fibroblast proliferation1,2,3
  • Reduced pH interferes with the activity of proteases, but does not permanently deactivate them1 It does not support bacterial growth.
  • CADESORB with soy composition does not promote bacterial growth

Promotes the removal of moist necrotic plaques in chronic wounds5,6,7

- By creating an optimal environment, it helps to overcome obstacles on the path to wound healing

Absorbency5,6,7

  • Absorbs wound secretion and converts it into a soft, moist gel
  • Maintains the optimum moist environment needed for wound healing by the simultaneous application of a suitable secondary dressing

Easy to use

  • Soft and flexible
  • Biodegradable
Categories , , , Tag Brand:
Catalogue numberSizeNo. of pieces in the box
6600005420 g1
6600005520 g2
660000565 × 10 g5
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1. Smith & Nephew data on file report 04100202 2. Trengove, N.J., Stacey M.C., MacAuley, S., et al. Analysis of the acute and chronic wound environments: the role of proteases and their inhibi-tors. Wound repair Regen, 1999; 7(6): 442-52. 3, Cullen, B., Smith, R., McCulloch, E.,Silcock, D., Morrison, L., Mechanism of action of PROMOGRAN, a protece modulating matrix, for the treatment of diabetic foot ulcers Wound Repair Regen 0000- 10111-16-25 4 SmithNenhew date on file report 0410018. 5, Troëng, T., Skog, t., Armesjo, B. A randomized multi-centre trial to compare the efficacy of cadexomer iodine and standard trealment ir the management of chronic venous ulcers in outpatients, in Cadexomer lodine, J.A. Fox and H. Fischer, Editors 1983, Schattauer Verlag: Stuttgart. P. 43-50.

6. Moberg, S., Hoffman, L., Grennert, M.L., Holst, A. A randomized trial of cadxomer iodine in decubitus ulcers. J. Am Geriatr Soc, 1983; 31(8): 462-5. 7. Ormiston, M.C., Seymour, M.T., Venn, G.E. Cohen, R.I., Fox, J.A. Controlled trial of iodosorb in chronic venous ulcers. Br Med J (Clin Res Edi. 1985: 291(6491): 308-10

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